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Department of Infectious Diseases

Vincent Starai

PhD
Assistant Professor
Department of Microbiology
Email: .(JavaScript must be enabled to view this email address)


Research Interests

  • Characterizing intracellular bacterial pathogen ‘survival’ factors which alter host cell membrane dynamics and fusion pathways
  • Eukaryotic membrane fusion biochemistry​

Selected Publications

Search PubMed for “starai vj”

  • Bennett TL, Kraft SM, Reaves BJ, Mima J, O’Brien KM, Starai VJ. LegC3, an Effector Protein from Legionella pneumophila, Inhibits Homotypic Yeast Vacuole Fusion In Vivo and In Vitro. PLoS One. 2013;8(2):e56798.
  • Starai VJ, Hickey CM, Wickner W. HOPS proofreads the trans-SNARE complex for yeast vacuole fusion. Mol Biol Cell. 2008 Jun;19(6):2500-8. doi: 10.1091/mbc.E08-01-0077.
  • Starai VJ, Jun Y, Wickner W. Excess vacuolar SNAREs drive lysis and Rab bypass fusion. Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13551-8. Epub 2007 Aug 15.
  • Jun Y, Thorngren N, Starai VJ, Fratti RA, Collins K, Wickner W. Reversible, cooperative reactions of yeast vacuole docking. EMBO J. 2006 Nov 15;25(22):5260-9.
  • Starai VJ, Garrity J, Escalante-Semerena JC. Acetate excretion during growth of Salmonella enterica on ethanolamine requires phosphotransacetylase (EutD) activity, and acetate recapture requires acetyl-CoA synthetase (Acs) and phosphotransacetylase (Pta) activities. Microbiology. 2005 Nov;151(Pt11):3793-801.
  • Starai VJ, Gardner JG, Escalante-Semerena JC. Residue Leu-641 of Acetyl-CoA synthetase is critical for the acetylation of residue Lys-609 by the Protein acetyltransferase enzyme of Salmonella enterica. J Biol Chem. 2005 Jul 15;280(28):26200-5.
  • Starai VJ, Thorngren N, Fratti RA, Wickner W. Ion regulation of homotypic vacuole fusion in Saccharomyces cerevisiae. J Biol Chem. 2005 Apr 29;280(17):16754-62.
  • Starai VJ, Escalante-Semerena JC. Acetyl-coenzyme A synthetase (AMP forming). Cell Mol Life Sci. 2004 Aug;61(16):2020-30. Review.
  • Starai VJ, Escalante-Semerena JC. Identification of the protein acetyltransferase (Pat) enzyme that acetylates acetyl-CoA synthetase in Salmonella enterica. J Mol Biol. 2004 Jul 23;340(5):1005-12.
  • Starai VJ, Takahashi H, Boeke JD, Escalante-Semerena JC. A link between transcription and intermediary metabolism: a role for Sir2 in the control of acetyl-coenzyme A synthetase. Curr Opin Microbiol. 2004 Apr;7(2):115-9. Review.

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