The following glomerular diseases occur in domestic animals:
What is the definition of glomerulitis?
What is the definition of glomerulonephritis?
Glomerular damage usually induces tubular or interstitial damage too. One reason for this is that blood flow to the tubules goes through the glomerulus first, therefore inflammatory mediators will be carried to tubules, In addition, glomerular lesions may limit blood flow to the tubules resulting in ischemic damage.
We use modifiers, membranous, proliferative, membranoproliferative, or exudative to further characterize the glomerular lesion.
Membranous means that thickening of the glomerular capillary basement membrane is the primary change.
Proliferative means there is an increase in cellularity of the mesangium and membranoproliferative means there is a combination of the two.
Exudative means the glomerulus is filled with infammatory cells, usually neutrophils. This represents a very acute lesion.
GLOMERULOSCLEROSIS means that there is an abnormal increase in mesangial matrix.
What is glomerular amyloidosis?
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