S. Mark Tompkins
About S. Mark Tompkins
S. Mark Tompkins, PhD, received his doctorate in immunology from Emory University and then studied immune mechanisms of antigen- and virus-induced autoimmune diseases as a National Multiple Sclerosis Society Postdoctoral Fellow at Northwestern University Medical School. In 2002, Dr. Tompkins joined the Center for Biologics Evaluation and Research at the FDA as a Research Fellow, focusing on influenza virus vaccines and therapies.
Dr. Tompkins joined the University of Georgia College of Veterinary Medicine in 2005, where he is a member of a NIAID Center of Excellence for Influenza Research and Surveillance. In 2012, he was awarded a Senior Fulbright Scholar’s Award to work with the Australian Animal Health Laboratories in Geelong, Australia for six months. In 2016, Dr. Tompkins joined UGA’s newly established Center for Vaccines and Immunology to collaborate with members on cutting edge vaccines for infectious disease.
His research focuses on understanding the emergence, pathogenesis, prevention, and treatment of influenza viruses. These studies include surveillance for influenza virus in animal populations, susceptibility of different species to influenza infection, and influenza virus evolution. Areas of research include dissecting virus-host interactions at the cellular and host level and exploiting these interactions to collaboratively develop novel vaccines, antiviral drugs, and treatments for human and animal use.
- PhD (1997), Immunology, Emory University
- BS (1990), Microbiology, University of Illinois
- Immune response to influenza virus infection
- Development of novel vaccines and therapeutics for seasonal and pandemic influenza
- Anti-viral RNA interference
- Li Z, Gabbard JD, Mooney A, Gao X, Chen Z, Place RJ, Tompkins SM, He B. Single Dose Vaccination Of A Recombinant Parainfluenza Virus 5 Expressing NP From H5N1 Provides Broad Immunity Against Influenza A Viruses. J Virol. 2013 Mar 20.
- Mooney AJ, Tompkins SM. Experimental vaccines against potentially pandemic and highly pathogenic avian influenza viruses. Future Virol. 2013 Jan 1;8(1):25-41.
- Laing EM, Tripp RA, Pollock NK, Baile CA, Della-Fera MA, Rayalam S, Tompkins SM, Keys DA, Lewis RD. Adenovirus 36, adiposity, and bone strength in late-adolescent females. J Bone Miner Res. 2013 Mar;28(3):489-96.
- Perwitasari O, Yan X, Johnson S, White C, Brooks P, Tompkins SM, Tripp RA. Targeting organic anion transporter 3 with probenecid as a novel anti-influenza a virus strategy. Antimicrob Agents Chemother. 2013 Jan;57(1):475-83.
- Mooney AJ, Li Z, Gabbard JD, He B, Tompkins SM. Recombinant parainfluenza virus 5 vaccine encoding the influenza virus hemagglutinin protects against H5N1 highly pathogenic avian influenza virus infection following intranasal or intramuscular vaccination of BALB/c mice. J Virol. 2013 Jan;87(1):363-71.
- Li Z, Mooney AJ, Gabbard JD, Gao X, Xu P, Place RJ, Hogan RJ, Tompkins SM, He B. Recombinant parainfluenza virus 5 expressing hemagglutinin of influenza A virus H5N1 protected mice against lethal highly pathogenic avian influenza virus H5N1 challenge. J Virol. 2013 Jan;87(1):354-62.
- Bakre A, Mitchell P, Coleman JK, Jones LP, Saavedra G, Teng M, Tompkins SM, Tripp RA. Respiratory syncytial virus modifies microRNAs regulating host genes that affect virus replication. J Gen Virol. 2012 Nov; 93(Pt 11):2346-56.
- Driskell EA, Jones CA, Berghaus RD, Stallknecht DE, Howerth EW, Tompkins SM. Domestic cats are susceptible to infection with low pathogenic avian influenza viruses from shorebirds. Vet Pathol. 2013 Jan;50(1):39-45.
- Driskell EA, Pickens JA, Humberd-Smith J, Gordy JT, Bradley KC, Steinhauer DA, Berghaus RD, Stallknecht DE, Howerth EW, Tompkins SM. Low pathogenic avian influenza isolates from wild birds replicate and transmit via contact in ferrets without prior adaptation. PLoS One. 2012;7(6):e38067.
- Meliopoulos VA, Andersen LE, Brooks P, Yan X, Bakre A, Coleman JK, Tompkins SM, Tripp RA. MicroRNA regulation of human protease genes essential for influenza virus replication. PLoS One. 2012;7(5):e37169.