Site, Distribution, and Terminology of Edema
Sometimes the site of edema accumulation is critical.
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This photomicrograph depicts the brain from a dog that was hit by a car and sustained cranial trauma. Edema is present, but somewhat difficult to recognize because the fluid contains very little protein and thus is not stained.

How do we know there is edema? The spaces around vessels (asterisks) are widened because they were distended by the edema. Headache and then some ....

This frog had a septicemia resulting in total body edema. There is accumulation of fluid EVERYWHERE - this is called generalized edema.
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ANASARCA = generalized massive edema affecting all parts of the body. This term is usually reserved to refer to massive edema of the FETUS and is not commonly used elsewhere.

When fluid accumulates in a limited area, it is "localized edema". Edema distributed throughout the body as depicted in these puppies is referred to as "generalized edema".

The prefix "hydro" is often added to the anatomic site to denote edema in a particular area. Examples include hydroperitoneum (ascites), hydrothorax, hydrosalpinx, hydropericardium, and hydrocephalus. The word "hydrops" is sometimes used in a manner similar to the prefix "hydro", e.g. "hydrops of the gall bladder" or "hydrops amnion". Have you ever heard of the term "dropsy"? It is an old-fashioned word for chronic heart failure and got its origins from the generalized edema that heart failure can cause.

Hydrops Allantois in a ewe. The uterus (arrowheads) is massively distended by excessive allantoic fluid.
Opened thorax of a cat. What will you call this and what might be a pathogenesis?
And, how about this one? Horse dropped over dead; pericardial sac has WAY too much fluid..... Fluid around the heart is called.....
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