This is the most difficult unit in the entire General Pathology course.
Hemostasis is governed by a complex and interconnected series of chemical and cellular reactions. Unfortunately, it is an extremely important process and your grasp of it is essential for understanding many aspects of clinical medicine and therapies.
Definition: Hemostasis is the normal state of balance maintained in the blood to control hemorrhage and inhibit thrombosis.

At the left is a thrombus within a small blood vessel in the lung. This is a reflection of hemostasis gone awry.

We will cover hemostasis using the following categories:

  • platelets and the formation of the primary hemostatic plug
  • clotting factors and the formation of the permanent hemostatic plug, including intrinsic and extrinsic pathways
  • inhibition of coagulation
  • fibrinolysis
  • hemostatic disorders
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