in Normal Blood Flow
|Abnormal blood flow
resulting in eddy currents, turbulence or blood stasis disrupts the laminar
flow of blood, bringing platelets in close contact with the vascular
wall. If coagulation factors are activated, they may not be cleared as
quickly if there is stasis or turbulence. Turbulence may
cause endothelial injury resulting in release of tissue factor.
heartworms can cause endothelial damage and at the same time
cause turbulence when large numbers occupy the right heart and
pulmonary arteries. What
|Venous stasis is
a common cause of thrombosis, particularly in humans. Any partial or
complete occlusion or compression of venous return can result in thrombosis.
or cardiac valvular dysfunction create turbulence that may
result in thrombosis.