Cell Injury from DNA Damage

Remember the basic DNA structures???

Purines?

Pyramidines??

Well here’s a refresher course…

The bases are joined together along with a sugar backbone and phosphate to form DNA
DNA damage can occur in many different ways.

The causes of DNA damage can be either

  • intrinsic – damage from factors inside the cell, or
  • extrinsic – damage from factors outside the cell.
These changes all result in damage to the cell.
Let's look at intrinsic damage »