The research in my lab is focused on Plasmodium falciparum, the causative agent of malaria. The parasite uses a protein encoded by an antigenically variant gene family to bind receptors on host cells, allowing the parasites to avoid passage through the spleen. One member of this family encodes a protein […]
My research interests span the ecology, evolution, population dynamics, and molecular epidemiology of emerging infectious diseases. I am primarily interested in viral disease systems, such as influenza A virus, where transmission at individual (including between host species), population and global scales are difficult to observe or quantify.
I was born in Maracaibo, Venezuela, a very warm, colorful, coastal city with cultural and geographical importance for the development of the region. With no doubts, one of the most beautiful countries on the planet, not only for the natural and economic resources, but also for our lovely and diverse […]
My laboratory studies mechanisms of respiratory innate immunity supporting immune responses to pathogens or underlying pathogeneses of lung diseases. The first major project focuses on cystic fibrosis lung disease and studies host-pathogen interactions between neutrophils and respiratory pathogens, Pseudomonas aeruginosa, Staphylococcus aureus and Mycobacterium abscessus. The second main project investigates […]
Inflammation is necessary for efficient pathogen clearance, but inappropriate inflammation contributes to the pathogenesis of infectious and autoimmune diseases. The focus of the Watford lab is to gain a better understanding of immunoregulatory networks, especially at pulmonary and gastrointestinal barriers that represent major sites for pathogen entry. Current efforts are […]