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Patient Success Story: Winston

Posted by: Mary Ellen Luther

Owned by Mary Ellen Luther
Clarksville, TN

"When you saved Winston's life, you saved a member of our family. You saved a "brother" to my two children. You saved a piece of my heart."

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UGA researchers exploring the adaptation of diarrheal-causing Campylobacter jejuni in recent study

Team of UGA researchers exploring the adaptation of diarrheal-causing Campylobacter jejuni in recent study

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UGA research study explores resurgence of pertussis

A team of researchers including scientists from the University of Georgia has found that the resurgence of pertussis, more commonly known as whooping cough, in the U.S. is a predictable consequence of incomplete coverage with a highly effective vaccine. This finding goes against pervasive theories on why we are seeing a steady increase in the disease even though the vaccine is given at an early age.

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Dr. Wilkes’ lab research published in Journal of Veterinary Microbiology

Posted by: Noah Hill

Canine distemper virus (CDV) is an RNA virus of the genus Morbillivirus within the family Paramyxoviridae. CDV produces multi-systemic disease in dogs and other terrestrial carnivores. With the development of modified live vaccines in the 1950s and 1960 s, the disease, with a few exceptions, has been successfully controlled. However, recently the cases of CDV in vaccinated dogs have been increasing throughout the world, including the United States. There are many reasons that can lead to vaccine failure, including antigenic differences between the vaccine strains and the currently circulating wild-type strains. Currently, there are at least three genetically different CDV lineages circulating in the US. Therefore, in this study, we evaluated various wild-type CDV and vaccine isolates to determine if the genetic differences observed among various strains result in significant antigenic differences based on changes to the neutralizing epitopes. The results of a cross-neutralization assay revealed that there are antigenic differences among the tested CDV wild-type isolates as well as between the tested isolates and the vaccine strains currently used in the US. Therefore, these results suggest the need to develop an updated CDV vaccine.

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