Department of Population Health, Poultry Diagnostic and Research Center
Assistant Research Scientist, CRP-FLU Lab
- Host and viral factors that modulates pathogenesis of influenza and SARS-CoV-2
- Transmission and antigenicity of influenza
- Antiviral evaluation against influenza and SARS-CoV-2
- Development of vaccines against influenza for mammalian and avian species
Joaquin’s doctoral work was focused on the non-canonical protein synthesis mechanism in Retroviruses and other RNA viruses. Joaquin joined the Perez laboratory in 2018 as a Postdoctoral Research Associate and became an Assistant Research Scientist (non-tenure track faculty) in 2022. Since 2018, Joaquin has focused on the pathogenesis, transmission, antigenicity, and antiviral evaluation related to influenza and SARS-CoV-2 using a combination of in vitro and in vivo assays. In addition, Joaquin’s research interests are associated with developing influenza vaccines for mammalian and avian species.
Bachelor’s degree in biochemistry (2013). Pontificia Universidad Catolica de Chile (Santiago, Chile)
Ph.D. in Microbiology (2017). PhD in Microbiology. Universidad de Chile (Santiago, Chile)
Ad-hoc reviewer for the Journal of Virology, Emerging Microbes, and Infection, Microbiology Spectrum, Plos Pathogens, and Vaccines, among others.
Lectureer in several courses related to microbiology, virology, and eukaryotic gene expression for undergrad and graduate students.
Seibert B, Cáceres CJ, Carnaccini S, Cardenas-Garcia S, Gay LC, Ortiz L, Geiger G, Rajao DS, Ottesen E, Perez DR. Pathobiology and dysbiosis of the respiratory and intestinal microbiota in 14 months old Golden Syrian hamsters infected with SARS-CoV-2. PLoS Pathog. 2022 Oct 24;18(10):e1010734.
Cáceres CJ, Cardenas-Garcia S, Carnaccini S, Seibert B, Rajao DS, Wang J, Perez DR. Efficacy of GC-376 against SARS-CoV-2 virus infection in the K18 hACE2 transgenic mouse model. Sci Rep. 2021 May 5;11(1):9609.
Cáceres CJ, Cardenas-Garcia S, Jain A, Gay LC, Carnaccini S, Seibert B, Ferreri LM, Geiger G, Jasinskas A, Nakajima R, Rajao DS, Isakova-Sivak I, Rudenko L, Vincent AL, Davies DH, Perez DR. Development of a Novel Live Attenuated Influenza A Virus Vaccine Encoding the IgA-Inducing Protein. Vaccines (Basel). 2021 Jun 27;9(7):703.
Cáceres CJ, Hu Y, Cárdenas-García S, Wu X, Tan H, Carnaccini S, Gay LC, Geiger G, Ma C, Zhang QY, Rajao D, Perez DR, Wang J. Rational design of a deuterium-containing M2-S31N channel blocker UAWJ280 with in vivo antiviral efficacy against both oseltamivir sensitive and -resistant influenza A viruses. Emerg Microbes Infect. 2021 Dec;10(1):1832-1848.
Cáceres CJ, Angulo J, Lowy F, Contreras N, Walters B, Olivares E, Allouche D, Merviel A, Pino K, Sargueil B, Thompson SR, López-Lastra M. Non-canonical translation initiation of the spliced mRNA encoding the human T-cell leukemia virus type 1 basic leucine zipper protein. Nucleic Acids Res. 2019 Feb 20;47(3):1599.