Biography

Rodrigo Abreu

Center for Vaccines and Immunology
PhD
Postdoctoral Research Associate, Ross Lab

Biography

Rodrigo B. Abreu received his doctorate in infectious diseases from the University of Georgia in 2018 for his work on the impact of iron export in macrophages during tuberculosis infection. During his graduate years, Dr. Abreu showed that TLR signaling in macrophages can lead to intracellular iron sequestration in macrophages through redundant yet independent mechanism, and the relevance of such mechanisms for intracellular replication of siderophilic bacteria such Mycobacterium tuberculosis. To complement his training in innate immunology, he has recently joined Dr. Ross Lab at Center for Vaccines and Immunology, to work on the adaptive immune response to influenza in humans. As a Post-doctoral fellow, he will focus on the crosstalk of the adaptive and innate immune system during influenza infection or vaccination, with a particular interest in systems serology.

Research Interests

  • Activation of humoral immune response to influenza infection or vaccination
  • Antibody functionality and crosstalk with innate immune system
  • Impact of pre-immunity during influenza infection or vaccination

Educational Background

Bs (2008): Biology, University of Porto, Porto, Portugal

Ms (2011): Toxicology, University of Porto, Porto Portugal

PhD (2018) University of Georgia, Georgia, USA

Selected Publications

Abreu RB , Quinn FQ., Giri PG. Role of the hepcidin-ferroportin axis in pathogen mediated intracellular iron sequestration in human macrophages. Blood Adv., 2018 (in pub)

Abreu RB , Quinn FQ, Giri PG. Heparin inhibits intracellular Mycobacterium tuberculosis bacterial replication by reducing iron level in human macrophages. Scientific reports ,2018 (under revision)

Abreu RB , Quinn FQ, Giri PG. Interferon-γ promotes iron export in human macrophages to limit intracellular bacteria replication. Sientific reports, 2018 (in submission)