Poultry Diagnostic and Research Center
Assistant Professor
Biography
Dr Carnaccini obtained her DVM degree from the University of Bologna, Italy in 2012 and her PhD in Comparative Biomedical Sciences from the University of Georgia in 2020. Her PhD research focused on studying the molecular determinants of antigenicity of the H9 subtype of avian influenza virus. She also contributed to study pathobiology and transmission of various influenza A virus subtypes in vitro and in vivo. Dr Carnaccini is specialized in both poultry medicine and general pathology as a diplomate of the American College of Poultry Veterinarians and the American College of Veterinary Patologists, respectively. She is now an Assistant Professor at the Poultry Diagnostic and Research Center, Population Health Department of the University of Georgia. Her appointment includes routine diagnostic for poultry species, teaching veterinary students, graduate students and residents, and development of her own independent research program. Carnaccini’s research, currently focuses on avian influenza pathobiology, evolution at the level of the wildlife-poultry interface. Ongoing collaborations include testing of antivirals against SARS-CoV-2 and study the pathology and tissue tropism of SARS-CoV-2 in multiple animal models.
Selected Publications
1. Carnaccini S, Palmieri C, Stoute S, Crispo M, Shivaprasad HL Infectious laryngotracheitis of chickens: Pathologic and immunohistochemistry findings. Accepted in Veterinary Pathology. 2021. doi: 10.1177/03009858211035388.
2. Seibert B, Cáceres CJ, Cárdenas-García S, Carnaccini S, Geiger G, Rajão DS, Ottesen E, and Perez DR. Mild and severe SARS-CoV-2 infection induces respiratory and intestinal microbiome changes in the K18-hACE2 transgenic mouse model. Microbiology Spectrum. Vol. 9(1):e0053621. 2021.
3. Cáceres, CJ, Cárdenas-García S, Carnaccini S, Seibert B, Rajão DS, Wang J and Perez DR. Efficacy of GC-376 against SARS-CoV-2 virus infection in the K18-hACE2 transgenic mouse model. Sci Rep., 11(1):9609. 2021.
4. Phipps KL, Ganti K, Jacobs NT, Lee CY, Carnaccini S, White MC, Manandhar M, Pickett BE, Tan GS, Ferreri LM, Perez DR, Lowen AC. Collective interactions augment influenza A virus replication in a host-dependent manner. Nat Microbiol., 5(9):1158-1169. 2020.
5. Carnaccini S, Santos JJS, Obadan AO, Pantin-Jackwood MJ, Suarez DL, Rajão DS, Perez DR. Age-dependent pathogenesis of clade 2.3.4.4A H5N2 HPAIV in experimentally infected Broad Breasted White turkeys. Vet Microbiol., 231:183-190. 2019.
6. Carnaccini S, Shivaprasad HL, Stoute S, Bickford AA, Senties-Cué CG. Pathology and Tissue Distribution of a H5N8 Avian Influenza Virus from the 2014 California Outbreak in Quail. Avian Diseases, 61(1):70-76. 2017.
7. Carnaccini S, Lowenstine LJ, Sentíes-Cué CG, Nyaoke A, Bland M, Bickford AA, Shivaprasad HL, and Stoute ST. Trichodinosis associated with pathology of the reproductive tract in waterfowl. Avian Pathology, 45(4):418-25. 2016.
8. Carnaccini S, Shivaprasad HL, Cutler G, Bland M, Meng XJ, Kenney SP, Bickford AA, Cooper G, Charlton B, and Sentíes-Cué CG. Characterization of seven outbreaks of hemorrhagic hepatopathy syndrome in commercial pullets following the administration of a Salmonella Enteritidis bacterin in California. Avian Diseases, 60:33-43. 2016.
9. Carnaccini S, Ferguson-Noel NM, Black P, Chin RP, Bland M, Bickford AA and Sentíes-Cué CG. A novel Mycoplasma sp. associated with phallus disease in goose breeders: pathological and bacteriological findings. Avian Diseases, 60(2):437-43, 2016.
10. Carnaccini S, Crossley B, Breitmeyer R, Charlton BR, Bland M, Fowler K, De La Torre F, Torchetti MK, Wong S, Wilson D, Jones A, and Sentíes-Cué CG. Diagnosis and Control of a LPAI H5N8 Outbreak in a Japanese Quail (Coturnix c. japonica) Commercial Flock in Central Valley California. Avian Diseases, 59:344–348, 2015.
