Center for Vaccines and Immunology
Assistant Research Scientist
Biography
Ying Huang did her undergraduate and graduate studies in Veterinary Medicine and Virology at Jilin Agriculture University from 1999 to 2006. She received her doctorate from Jilin University in 2009 and finished her postdoctoral training in Chinese Center for Diseases Control and Prevention and the University of Georgia in 2012 and 2016, respectively. Her previous research focused on investigation of rabies virus pathogenesis, evaluation of immune responses induced by virus infection and development of novel vaccines for rabies prevention as well as for clinical rabies therapy. She had more than 26 publications and one book chapter. She joined the center for vaccine and immunology in the beginning of 2017, and she is working to develop vaccines for emerging infectious diseases.
Research Interests
- Development of vaccines against emerging infectious diseases
- Evaluation of the immune responses elicited by the vaccines
Educational Background
- PhD (2009), Molecular Virology, Jilin University, China
- MS (2006), Molecular Virology, Jilin Agriculture University, China
- BS (2003), Veterinary Medicine, Jilin Agriculture University, China
Selected Publications
- Huang Y, Chen Z, Huang J, Fu Z, He B. Parainfluenza virus 5 expressing the G protein of rabies virus protects mice after rabies virus infection. J Virol. 2015 Mar;89(6):3427-9.
- Yang Y, Huang Y, Gnanadurai CW, Cao S, Liu X, Cui M, Fu ZF. The inability of wild-type rabies virus to activate dendritic cells is dependent on the glycoprotein and correlates with its low level of the de novo-synthesized leader RNA. J Virol. 2015 Feb;89(4):2157-69.
- Chai Q, She R, Huang Y, Fu ZF. Expression of neuronal CXCL10 induced by rabies virus infection initiates infiltration of inflammatory cells, production of chemokines and cytokines, and enhancement of blood-brain barrier permeability. J Virol. 2015 Jan;89(1):870-6.
- Gnanadurai CW, Yang Y, Huang Y, Li Z, Leyson CM, Cooper TL, Platt SR, Harvey SB, Hooper DC, Faber M, Fu ZF. Differential Host Immune Responses after Infection with Wild-Type or Lab-Attenuated Rabies Viruses in Dogs. PLoS Negl Trop Dis. 2015 Aug 0;9(8):e0004023.
- Huang Y, Jiao S, Tao X, Tang Q, Jiao W, Xiao J, Xu X, Zhang Y, Liang G, Wang H. Met-CCL5 represents an immunotherapy strategy to ameliorate rabies virus infection. J Neuroinflammation. 2014 Aug 21;11:146.
- Huang CT, Li Z, Huang Y, Zhang G, Zhou M, Chai Q, Wu H, Fu ZF. Enhancement of blood-brain barrier permeability is required for intravenously administered virus neutralizing antibodies to clear an established rabies virus infection from the brain and prevent the development of rabies in mice. Antiviral Res. 2014 Oct;110:132-41.
- Yu P, Huang Y, Zhang Y, Tang Q, Liang G. Production and evaluation of a chromatographically purified Vero cell rabies vaccine (PVRV) in China using microcarrier technology. Hum Vaccin Immunother. 2012 Sep;8(9):1230-5.
- Du J, Tang Q, Huang Y, Rodney WE, Wang L, Liang G. Development of recombinant rabies viruses vectors with Gaussia luciferase reporter based on Chinese vaccine strain CTN181. Virus Res. 2011 Sep;160(1-2):82-8.
- Huang Y, Tang Q, Nadin-Davis SA, Zhang S, Hooper CD, Ming P, Du J, Tao X, Hu R, Liang G. Development of a reverse genetics system for a human rabies virus vaccine strain employed in China. Virus Res. 2010 Apr;149(1):28-35.
