Faculty Research Labs

Dr. Schank’s Lab

The Schank Lab studies the interaction between stress, neuropeptides, and drug seeking behavior. The primary receptor system that we study is the neurokinin-1 receptor (NK1R), and we examine the function that it plays in the extended amygdala brain circuitry. We aim to identify how these processes influence drug/alcohol seeking behavior, anxiety, and depression.

Research

Main projects in the lab include:

  • The neurocircuitry by which the NK1R mediates stress-induced reinstatement of alcohol seeking
  • The NK1R neurocircuitry that underlies the impact of social defeat stress on depression-like behavior and escalated alcohol consumption
  • The role of the NK1R in oxycodone self-administration, stress-induced reinstatement, and sex differences in drug seeking
  • The mechanisms of sex differences in aversion-resistant alcohol intake

Publications on MyNCBI