Influenza viruses are pathogens of great significance to public and animal health. Dr. Perez studies the changes that allow influenza viruses to jump animal species and cause disease in humans. Dr. Perez’s long-term goal is to provide a comprehensive map of molecular changes associated with animal-to-human (A2H) and human-to-human (H2H) transmission of influenza viruses. Such information is crucial to better prepare against influenza viruses with zoonotic potential and/or of pandemic concern. Dr. Perez’s laboratory uses a wide range of in vitro and in vivo approaches to better understand influenza virus host range and improve existing and/or develop new universal vaccines and antivirals. Dr. Perez contributions on the role of quail as a host for influenza viruses with expanded host range was one argument that led to banning live quail in Hong Kong poultry markets in 2002. Later, Dr. Perez’s group demonstrated the molecular aspects responsible for respiratory droplet transmission of avian influenza viruses of the H9 and H7 subtypes in ferrets (mammals). During 2005-2011, Dr. Perez was responsible for the program “Prevention and Control of Avian Influenza in the US”, a USDA-funded multi-institutional project with a comprehensive research and surveillance structure. Since 2007, The Perez’s lab is part of the NIAID-funded CEIRS Center for Research on Influenza Pathogenesis (CRIP), led by Dr. Adolfo Garcia-Sastre at Icahn School of Medicine at Mount Sinai, New York. In April 2015, Dr. Perez joined the Department of Population Health, University of Georgia as Georgia Research Alliance Distinguished Investigator and Caswell S Eidson Chair in Poultry Medicine within the Poultry Research and Diagnostic Center. Since 2017, Dr. Perez is also affiliated with the Center for Vaccines and Immunology.
- Emerging and Zoonotic Viral Diseases
- Host range and of pathogenesis and transmission of influenza viruses
- Development of alternative vaccines against influenza
- Development of influenza viruses as vaccine vectors
- Development of Orthmyxo and Paramyxo viruses as oncolytic agents
- Discovery of novel anti-viral strategies against Orthomyxo and Paramyxo viruses
- BSc (1989) Biochemistry, Universidad Nacional de Cordoba, Argentina
- PhD (1995) Molecular Virology, University of Nebraska Medical Center
- Associate Editor, RNA virus section, PLOS Pathogens (2014-present)
- Editorial Board, Journal of Virology (2007-present)
- Editor, Influenza Research and Treatment (2009-present)
- Editorial Board, Virology (2010-present)
- Guest Editor, “H5N1 Influenza Virus”, a special issue of Viruses (ISSN 1999-4915)
- Guest Editor, “H5N1”, a special issue of Virus Research (ISSN 0168-1702)
- Ad-hoc Reviewer for the journals Vaccine, Virus Genes, Avian Pathology, Analytical Chemistry, Journal of Virology, Virology, Virus Research, Journal of General Virology, Emerging Infectious Diseases, Avian Diseases, PNAS, among others.