Department of Physiology and Pharmacology
Associate Professor

Mitochondrial Physiology | Muscle Biology | Regenerative Rehabilitation


Research Interests

  • Regulation of mitochondrial bioenergetics with disease, injury, and exercise
  • Musculoskeletal remodeling after traumatic injury

Educational Background

  • BS Biology (2005) Wittenberg University
  • MS Muscle Physiology & Biochemistry (2007) Virginia Tech
  • PhD Rehabilitation Science (2011) University of Minnesota
    • Minor: Biochemistry, Molecular Biology & Biophysics

Teaching Experience

  • Neuromuscular Physiology
  • Mitochondrial Physiology
  • Exercise Physiology
  • The Physiology & Philosophy of Running

Selected Publications

  • Publications by Dr. Call may be found at PubMed
  • McFaline-Figueroa J, Schifino AG, Nichenko AS, Lord MN, Hunda ET, Winders EA, Noble EE, Greising SM, Call JA. Pharmaceutical Agents for Contractile-Metabolic Dysfunction After Volumetric Muscle Loss. Tissue Eng Part A. 2022 Aug 1; InPress
  • Lord MN, Heo JW, Schifino AG, Hoffman JR, Donohue KN, Call JA, Noble EE. Sexually Dimorphic Effects of a Western Diet on Brain Mitochondrial Bioenergetics and Neurocognitive Function. Nutrients. 2021 Nov 24;13(12).
  • Dalske KA, Raymond-Pope CJ, McFaline-Figueroa J, Basten AM, Call JA, Greising SM. Independent of physical activity, volumetric muscle loss injury in a murine model impairs whole-body metabolism. PLoS One. 2021;16(6):e0253629.
  • Corona BT, Call JA, Borkowski M, Greising SM. In Vivo Measurement of Hindlimb Dorsiflexor Isometric Torque from Pig. J Vis Exp. 2021 Sep 3;(175).
  • Nichenko AS, Sorensen JR, Southern WM, Qualls AE, Schifino AG, McFaline-Figueroa J, Blum JE, Tehrani KF, Yin H, Mortensen LJ, Thalacker-Mercer AE, Greising SM, Call JA. Lifelong Ulk1-Mediated Autophagy Deficiency in Muscle Induces Mitochondrial Dysfunction and Contractile Weakness. Int J Mol Sci. 2021 Feb 16;22(4).
  • Nichenko AS, Southern WM, Tehrani KF, Qualls AE, Flemington AB, Mercer GH, Yin A, Mortensen LJ, Yin H, Call JA. Mitochondrial-specific autophagy linked to mitochondrial dysfunction following traumatic freeze injury in mice. Am J Physiol Cell Physiol. 2020 Feb 1;318(2):C242-C252
  • Southern WM, Nichenko AS, Tehrani KF, McGranahan MJ, Krishnan L, Qualls AE, Jenkins NT, Mortensen LJ, Yin H, Yin A, Guldberg RE, Greising SM, Call JA. PGC-1α overexpression partially rescues impaired oxidative and contractile pathophysiology following volumetric muscle loss injury. Sci Rep. 2019 Mar 11;9(1):4079.
  • Ruehle MA, Stevens HY, Beedle AM, Guldberg RE, Call JA. Aggregate mesenchymal stem cell delivery ameliorates the regenerative niche for muscle repair. J Tissue Eng Regen Med. 2018 Aug;12(8):1867-1876.
  • Xie L, Yin A, Nichenko AS, Beedle AM, Call JA, Yin H. Transient HIF2A inhibition promotes satellite cell proliferation and muscle regeneration. J Clin Invest. 2018 Jun 1;128(6):2339-2355.

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