Department of Pathology, One Health Certificate

Animal Models of Human Disease | Neuropathology | Ocular Pathology


Research Interests

  • Neuropathology
  • Animal models of human disease (mucopolysaccharidosis IIIA carbohydrate-deficient glycoprotein syndrome, globoid cell leukodystrophy)

Dr. Carmichael’s main research emphasis has been on a group of inherited neurological diseases in dogs, including hepatocerebellar degeneration (HCD) of Bernese Mountain dogs and a cerebellar ataxia syndrome affecting Jack Russell terriers. Her research group has already developed a test for globoid cell leukodystrophy in Irish Setters and for mucopolysaccharidosis IIIA in wire haired dachshunds. Her studies in inherited neurological disease also extend to therapeutics and she is investigating the use of xenophobic stem cell transplants in a caprine model of MDSIIID. Her research group was the first to describe FeLV-associated myelopathy in cats.

Educational Background

  • Professor, DVM (1987) Tuskegee University
  • PhD (1993) The University of Georgia
  • Diplomate, American College of Veterinary Pathologists

Teaching Experience

  • Inherited diseases
  • General pathology
  • Oophthalmic pathology
  • Digestive pathology
  • Integumentary pathology

Selected Publications

  • ​Silverstein Dombrowski DC, KP Carmichael, Wang P, O’Malley TM, Haskins ME, Giger U. Mucopolysaccharidosis type VII in a German Shepherd Dog. J Am Vet Med Assoc. 224: 553-7, 532-3, 2004
  • K. P. Carmichael, D. Bienzle; J. J. McDonnell. Feline Leukemia Virus-associated Myelopathy in Cats. Veterinary Pathology. 39: 27-31, 2002
  • Carmichael, KP. Diagnostic features of polysaccharide storage myopathy. Comp Cont Ed, 22: 507-509; 2000
  • Aronovich EL, KP Carmichael, H Morizono, IG Koutlas, M Deanchimg, G Hoganson, A. Fischer, C Whitely. Canine Heparan Sulfate Sulfamidase and the Molecular Pathology Underlying Sanfilippo syndrome type A in Dachshunds. Genomics, 66: 2-7; 2000
  • Fisher A, Carmichael KP, Munnell JF, Jhabvala P, Thompson J, Matalon R, Wang P, Giger U. Heparan sulfamidase deficiency in a family of Dachshunds: A canine model of mucopolysaccharidosis IIIA (Sanfilippo A). Pediat Res 44: 74-82; 1998
  • Yang Y, Arbtan KD, Carmichael KP, Orlando R. Is canine hepatocerebellar degeneration syndrome an animal model for carbohydrate-deficient glycoprotein syndrome in humans? An example of sequencing glycoprotein glycans with mass spectroscopy. Rapid Commun Mass Spectrom 12: 571-579; 1998
  • Carmichael KP, Miller M, Miller BE, Fisher A, Rawlings CA, Oliver JE. Clinical, hematologic, and biochemical findings of a syndrome in Bernese Mountain Dogs characterized by hepatocerebellar degeneration. J Amer Vet Med Assoc 208: 1277-1279, 1996
  • Additional publications by Dr. Carmichael may be found at PubMed.

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