Department of Pathology
Anatomic Pathology, IDIS Adjunct Faculty, Professor
Expertise
Animal Models of Human Disease | Disease Pathogenesis | Disease Physiology | Mycobacterial Diseases | Pathology of Filarial Diseases | Vector-Borne Diseases | Zoonotic Diseases
Biography
Research Interests
- Immunomodulatory effects of mycobacterial cell wall lipids
- Pathogenesis of granulomatous diseases
- Intramacrophagic bacterial survival
- Animal models of granulomatous diseases
- Pathology of Nematode Infections
Educational Background
- BS (1991) Duke University
- MLS (1995) North Carolina State University
- DVM (1999) North Carolina State University
- MS (2002) Purdue University
- PhD (2008) Cornell University
- Diplomate, American College of Veterinary Pathologists (2002)
Selected Publications
- Gupta, T., Lagatta, M., Helms, S., Pavlicek, R., Owino, S.O., Sakamoto, K., Nagy, T., Harvey, S.B., Papania, M., Schultz, K., Quinn, F.D., and R.K. Karls. Evaluation of a temperature-restricted, mucosal tuberculosis vaccine in guinea pigs. Tuberculosis. 2018:113:179-188.
- Wong, J.K., Chambers, L.C., Elsmo, E.J., Jenkins, T.L., Howerth, E.W., Phillips, A.E., Sánchez, S., and Sakamoto. Burkholderia cepacia outbreak associated with contaminated chlorhexidine 2% scrub in five cats (2012-2014). J Vet Diagn Invest. 2018:30(5):763-9.
- Novakowski, K.E. Han, S., Dorrington, M.G., Pelka, P., White, P., Hyunh, A., Guarne, A., Sakamoto, K., and D.M.E. Bowdish. Naturally-occurring Transcript Variants of MARCO Reveal the SRCR Domain is Critical for Ligand Binding and Uptake. Immun Cell Biol. 2016:94(7):646-55.
- Watson, M.K., Cazzini, P., Mayer, J., Gottdenker, N., Reavill, D., Parry, N., Fox, J.G., and Sakamoto. Histopathology and Immunohistochemistry of Severe Inflammatory Bowel Disease Versus Lymphoma in the Ferret (Mustela putorius furo). J Vet Diagn Invest. 2016:28(3):198-206.
- Edwards, E.E. Garner, B., Williamson, L.H., Storey, B., Gottdenker, N., and Sakamoto. Pathology of Haemonchus contortus in New World camelids in Georgia: a retrospective study (2002 – 2013). J Vet Diagn Invest.2016:28(2):105-9.
- Chen, X., Sakamoto, K., Quinn, F., Chen, H., and Z. Fu. Lack of intracellular replication of tuberculosis and M. bovis BCG caused by delivering bacilli to lysosomes in murine brain microvascular endothelial cells. Oncotarget. 2015:6(32):32456-32467.
- Budischak, S.A., Sakamoto, K., Megow, L., Cummings, K., Urban, J., and V. Ezenwa. Resource limitation alters the consequences of coinfection for both hosts and parasites. Int J Parasit. 2015:45(7):455-63.
- Cazzini, P., Frontera-Acevedo, K., Garner, B., Howerth, E., Torres, B., Northrup, N., and Sakamoto. Morphologic, Molecular, and Ultrastructural Characterization of a Feline Synovial Cell Sarcoma and Derived Cell Line. J Vet Diagn Invest. 2015:27(3):369-76.
- Frontera-Acevedo, K. and Sakamoto. Local Pulmonary Immune Responses in Domestic Cats Naturally Infected with Cytauxzoon felis. Vet Immunol and Immunopathol. 2015:163(1-2):1-7.
- Frontera-Acevedo, K., Brown, H.M., Peterson, S., Creevy, K., Garner, B., Balsone. N., Dugan, M., Makemson, C., Sellers, L.B., and K. Sakamoto. 2013. Systemic immune response in Cytauxzoon felis-infected domestic cats. Amer J Vet Res. 75(6):901-9.
