Organoid Focused
Sahoo, D.K.; Martinez, M.N.; Dao, K.; Gabriel, V.; Zdyrski, C.; Jergens, A.E.; Atherly, T.; Iennarella-Servantez, C.A.; Burns, L.E.; Schrunk, D.; et al. Canine Intestinal Organoids as a Novel In Vitro Model of Intestinal Drug Permeability: A Proof-of-Concept Study. Cells 2023, 12, 1269. https://doi.org/10.3390/cells12091269
Gabriel, V., Zdyrski, C., Sahoo, D. K., Dao, K., Bourgois-Mochel, A., Kopper, J., Zeng, X. L., Estes, M. K., Mochel, J. P., Allenspach, K. Standardization and Maintenance of 3D Canine Hepatic and Intestinal Organoid Cultures for Use in Biomedical Research. <em>J. Vis. Exp.</em> (179), e63515, doi:10.3791/63515 (2022).
Canine Intestinal Organoids in a Dual-Chamber Permeable Support System
Gabriel, V., Zdyrski, C., Sahoo, D. K., Dao, K., Bourgois-Mochel, A., Atherly, T., Martinez, M. N., Volpe, D. A., Kopper, J., Allenspach, K., Mochel, J. P. Canine Intestinal Organoids in a Dual-Chamber Permeable Support System. <em>J. Vis. Exp.</em> (181), e63612, doi:10.3791/63612 (2022).
Derivation of adult canine intestinal organoids for translational research in gastroenterology
Chandra, L., Borcherding, D.C., Kingsbury, D. et al. Derivation of adult canine intestinal organoids for translational research in gastroenterology. BMC Biol 17, 33 (2019). https://doi.org/10.1186/s12915-019-0652-6
Ambrosini YM, Park Y, Jergens AE, Shin W, Min S, Atherly T, et al. (2020) Recapitulation of the accessible interface of biopsy-derived canine intestinal organoids to study epithelial-luminal interactions. PLoS ONE 15(4): e0231423. https://doi.org/10.1371/journal.pone.0231423
Bedos, L., Wickham, H., Gabriel, V., Zdyrski, C., Allbaugh, R. A., Sahoo, D. K., Sebbag, L., Mochel, J. P., & Allenspach, K. (2022). Culture and characterization of canine and feline corneal epithelial organoids: A new tool for the study and treatment of corneal diseases. Frontiers in Veterinary Science, 9. https://doi.org/10.3389/fvets.2022.1050467
Canine Focused
Ahmed, BH, Zdyrski, C, Cheville, J, et al. Role of the tumour microenvironment in bladder cancer pathogenesis and value of the reverse translational approach: a tale of two species. Clin Transl Disc. 2023; 3: 1-19. https://doi.org/10.1002/ctd2.235
Allenspach, K.; Sung, C.-H.; Ceron, J.J.; Peres Rubio, C.; Bourgois-Mochel, A.; Suchodolski, J.S.; Yuan, L.; Kundu, D.; Colom Comas, J.; Rea, K.; et al. Effect of the Probiotic Bacillus subtilis DE-CA9TM on Fecal Scores, Serum Oxidative Stress Markers and Fecal and Serum Metabolome in Healthy Dogs. Vet. Sci. 2023, 10, 566. https://doi.org/10.3390/vetsci10090566
Díaz-Regañón, D.; Gabriel, V.; Livania, V.; Liu, D.; Ahmed, B.H.; Lincoln, A.; Wickham, H.; Ralston, A.; Merodio, M.M.; Sahoo, D.K.; et al. Changes of Enterocyte Morphology and Enterocyte: Goblet Cell Ratios in Dogs with Protein-Losing and Non-Protein-Losing Chronic Enteropathies. Vet. Sci. 2023, 10, 417. https://doi.org/10.3390/vetsci10070417
Sahoo, D.K.; Allenspach, K.; Mochel, J.P.; Parker, V.; Rudinsky, A.J.; Winston, J.A.; Bourgois-Mochel, A.; Ackermann, M.; Heilmann, R.M.; Köller, G.; et al. Synbiotic-IgY Therapy Modulates the Mucosal Microbiome and Inflammatory Indices in Dogs with Chronic Inflammatory Enteropathy: A Randomized, Double-Blind, Placebo-Controlled Study. Vet. Sci. 2023, 10, 25. https://doi.org/10.3390/vetsci10010025
